PHARMACEUTICAL SOLUTIONS
ZPI PHARMA MANNITOL | Mannitol 17.5% & Sorbitol 2.5% w/v Infusion (500ml)
The ZPI PHARMA MANNITOL is a specialized, sterile, and non-pyrogenic hypertonic solution designed for osmotic diuresis. This potent combination of Mannitol and Sorbitol is engineered to rapidly reduce fluid pressure in critical clinical scenarios, particularly involving the brain and eyes, while promoting renal function.
FULL DESCRIPTION
The ZPI PHARMA MANNITOL is a specialized, sterile, and non-pyrogenic hypertonic solution designed for osmotic diuresis. This potent combination of Mannitol and Sorbitol is engineered to rapidly reduce fluid pressure in critical clinical scenarios, particularly involving the brain and eyes, while promoting renal function.
Product Composition
Each 100 mL contains:
Total Concentration: 20% w/v Osmotic Active Solutes.
Key Features
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Dual-Active Osmotic Formula: The inclusion of Sorbitol alongside a high concentration of Mannitol helps maintain the solution’s stability and enhances the osmotic gradient for effective fluid shift.
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Rapid Pressure Reduction: Designed to quickly draw excess fluid from intracellular compartments into the vascular system to be excreted by the kidneys.
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Crystallization Resistant: Formulated to minimize the natural tendency of high-concentration Mannitol to crystallize at room temperature.
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Premium Quality Standards: Manufactured under strict aseptic conditions to ensure a sterile and non-pyrogenic product for intravenous use.
Clinical Indications
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Intracranial Pressure (ICP): Used to reduce elevated pressure in the skull caused by cerebral edema or head injury.
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Intraocular Pressure (IOP): Indicated for the reduction of high pressure within the eye, often during or before ophthalmic surgery or in acute glaucoma.
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Acute Renal Failure: Promotes the excretion of toxins and helps maintain urine flow (diuresis) in patients with acute oliguria (low urine output).
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Toxic Substance Excretion: Aids in the rapid elimination of certain drugs or toxins from the body through the kidneys.
Storage & Safety
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Crystallization Note: High concentrations of Mannitol may crystallize if exposed to low temperatures. If crystals are present, warm the bag in a water bath or incubator and shake gently until dissolved before administration.
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Single-Use Container: Intended for a single infusion. Discard any unused portion.
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Inspection: Use only if the solution is clear and the container is undamaged.
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Storage: Store at controlled room temperature ( to ). Avoid extreme cold.
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Prescription Only: This is a high-alert medication and must be administered strictly under the supervision of a registered medical practitioner.
Manufactured by: ZPI Pharma Jalozai Industrial Estate, Nowshera.